Preview the Week 15 matchup between the Seattle Seahawks and Indianapolis Colts with predictions, odds, over/under, spread, betting lines and more.

Dec 7, 2025; Atlanta, Georgia, USA; Seattle Seahawks cornerback Devon Witherspoon (21) celebrates with safety Julian Love (20) after an interception against the Atlanta Falcons in the fourth quarter at Mercedes-Benz Stadium. | Brett Davis-Imagn Images

All of football wants to know how the 44-year-old quarterback who hasn’t played in five years will do against Mike Macdonald’s defense.

Seattle residents planning to attend the Seahawks-Colts game should prepare for a cloudy Sunday with morning showers and continued flood concerns as a warning remains in effect, according to AccuWeather.

This article was originally published on www.si.com/nfl/seahawks/onsi as Why Colts matchup is a must-win game for the Seahawks. The Seattle Seahawks face a massive game in Week 15 as they host Jonathan Taylor and the Indianapolis Colts.

We at Seahawks Wire aim to help you look forward to Sunday’s game, but our hearts are with every community affected by the state's floods this week.

Ryan Clark unloaded on the Indianapolis Colts over the news that they will play Philip Rivers against the Seattle Seahawks.

General manager John Schneider chose the grind today, with the team announcing a flurry of roster and practice squad transactions going into Sunday's game again

No, Philip Rivers will not continue to haunt the Seahawks like he has in the past.