The San Francisco 49ers on Thursday had a true rarity to open the day's practice. ESPN's Nick Wagoner reported every member of the 49ers' active roster was on hand to open the session. That is a dramatic change for a 49ers club that has been battling major injury issues since training camp.

If the week of work goes well, quarterback Brock Purdy will start for the 49ers. He hasn’t played since a Week 4 loss to the Jaguars after injuring his toe in Week 1 and missing the next two games. The full details of their injury report are below. Starters are noted with an asterisk.

San Francisco 49ers quarterback Brock Purdy is officially back. 49ers head coach Kyle Shanahan said Thursday that Purdy is set to start against the Arizona Cardinals on Sunday after recovering from a turf toe injury, per Matt Maiocco of NBC Sports Bay Area.

Linebacker Josh Sweat was a non-participant on the latest Cardinals injury report for their Week 11 matchup against the 49ers.

The San Francisco 49ers have been waiting for Brandon Aiyuk to play in 2025, but there's a chance he doesn't return from his injury

Here is how the 49ers (6-4) graded in Sunday’s 42-26 home loss to the (7-2): PASS OFFENSE: B. Mac Jones’ three touchdown strikes obviously wer

Staying up to date on NFL injury news is of the utmost importance for fantasy football success. The article below tracks all fantasy-relevant players currently listed on their team's injury report, and provides fantasy managers with actionable recommendations as new information rolls in.

Christmas came early on the NFL schedule with a Week 11-stocking stuffed to the brim with tantalizing matchups.