The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
This article is based on a poster originally authored by Weiping Sun, Xing Zhang, Zhaolu Yan, Chen Yu, Spencer Chiang, and Tianfu Zhang. Immunotherapy is an advanced and widely used treatment due to ...
X™ T-Cell Transduction Sponge is honored in the Lab Research Tools category of the 2025 Top Innovations contest.
Approximately 9.5 million people globally live with type 1 diabetes, a chronic autoimmune disease where T cells from the body ...
ZURICH-SCHLIEREN, Switzerland and CONCORD, Mass., Nov. 07, 2024 (GLOBE NEWSWIRE) -- Molecular Partners AG (SIX: MOLN; NASDAQ: MOLN), a clinical-stage biotech company developing a new class of ...
Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...
HPV, a very common virus, is found to hijack the body's cells to directly drive skin cancer growth, even after surgeries and ...
Watch the 'What This Means' video hereFeaturing Company’s second-generation T-Cell Engager program and advantages over first-generationCompany’s ...
Xilio Therapeutics announces collaboration with AbbVie for tumor-activated immunotherapies, receiving $52 million upfront, extending cash runway to 2026. Xilio Therapeutics, Inc., a clinical-stage ...
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