Familial neurohypophysial diabetes insipidus (FNDI) characterized by progressive polyuria is mostly caused by mutations in the gene encoding neurophysin II (NPII), which is the carrier protein of the ...

Arginine vasopressin (AVP), also known as antidiuretic hormone, is a nonapeptide secreted from the posterior pituitary gland. The primary stimulus for the secretion of AVP is a rise in serum ...

People who have syndrome of inappropriate antidiuretic hormone secretion (SIADH) produce excessive amounts of antidiuretic hormones. It leads to the body developing an imbalance of sodium and water.

A blood test for copeptin, a precursor of antidiuretic hormone (ADH, vasopressin), differentiates between "harmless" polydipsia-polyuria and diabetes insipidus more quickly and accurately than a ...

Eleven of 13 patients with far advanced chronic renal disease of diverse etiologies were found to have urine that remained hypotonic to plasma in spite of the administration of a supramaximal dose of ...

Tolvaptan is a vasopressin receptor antagonist. Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron. Blocking ...

Cranial diabetes insipidus is a rare condition that results in persistent thirst and frequent urination. It occurs due to problems with arginine vasopressin (AVP), a hormone that plays a role in ...