Mycobacterium microti, the vole bacillus, which was used as a live vaccine against tuberculosis until the 1970s, confers the same protection in humans as does Mycobacterium bovis bacille ...

A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world's deadliest infectious disease. In the new study, a team ...

This is a preview. Log in through your library . Abstract Protection against Mycobacterium tuberculosis not only depends on CD4⁺T helper type 1 (Th1) cells but, also, on CD8⁺ T cells. Interleukin (IL) ...

Restoration of genes lost during the original attenuation of the commonly used BCG tuberculosis vaccine enhances the ability of a recombinant strain to protect against Mycobacterium tuberculosis. In ...

Several animal models have been developed and characterized, and they have been invaluable for identifying and characterizing mechanisms of protective immunity to M. tuberculosis. However, the ...

Tuberculosis remains a major health problem throughout the world causing large number of deaths. Effective disease control and eradication programs require the identification of major antigens ...

Niigata, Japan - Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb); the leading cause of human death due to a single pathogen before the emergence of SARS-CoV-2. In ...

A clever new tuberculosis vaccine has shown promise in trials in mice. If it succeeds, it will be the first new TB vaccine in a century. With the rise of multidrug resistant tuberculosis, the ...

A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions ...

While Bacillus Calmette-Guérin is the only approved tuberculosis vaccine, its variable efficacy, along with the rise of drug-resistant TB, means there is always room for an updated shot. A new ...