Human articular cartilage contains a population of stem or progenitor cells that can be isolated and characterized in vitro on the basis of having self-renewal, multilineage differentiation and ...

In this Review we describe three approaches for cartilage tissue repair at the rheumatology–orthopaedics interface: disease-modifying osteoarthritis (OA) drug (DMOAD) treatment; cell-based therapies, ...

Cartilage, a connective tissue found throughout the body, is critical to the function of our joints. Tough yet flexible, it supports load and enables frictionless ...

Osteoarthritis (OA) is the most prevalent musculoskeletal disease that afflicts millions of people worldwide. It is characterized by the irreversible breakdown of the extracellular matrix (ECM) of ...

University of California, San Diego (UCSD) bioengineers have fabricated cartilage tissue which for the first time mimics the multi-layered structure and cellular functions of natural articular ...

Can nondestructive MRI provide a measurement of cartilage function? The delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) index is highly correlated to mechanical stiffness, and, although not as ...

Researchers at the University of Southampton and the Centre for Human Development, Stem Cells, and Regeneration have developed a new method to generate human cartilage tissue from stem cells. The ...

Cartilage is an important structural component of the body. It is a firm tissue but is softer and much more flexible than bone. Cartilage is a connective tissue found in many areas of the body ...

Allograft or autograft osteoarticular transplants are useful tools for treating full-thickness articular cartilage lesions of the knee, according to a prospective analysis of 43 patients. “The current ...

A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new UBC research. Mimicking articular cartilage, found ...

Autologous chondrocyte implantation (ACI) is a two-step surgical procedure to restore cartilage around a joint and treat cartilage defects. Cartilage is the connective tissue found throughout the body ...