Figure 1: Clathrin was targeted to the mitotic spindle of NRK cells. Figure 2: Clathrin was targeted to the mitotic spindle via the N-terminal domain of the heavy chain. Does prolonged mitosis in ...

Clathrin light chain (CLC) subunits in vertebrates are encoded by paralogous genes CLTA and CLTB, and both gene products are alternatively spliced in neurons. To understand how this CLC diversity ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins ...

Endocytosis is the process by which cells take in molecules from their surroundings. Clathrin-dependent endocytosis requires the recruitment of clathrin to help curve the plasma membrane into the ...

Our lab is interested in the molecular mechanisms of cargo sorting along the endocytic pathway with particular emphasis on the regulation of the clathrin coated vesicle cycle by rab5 and reversible ...