A new statistical framework could speed up the search for rare mutations that cause common diseases, helping researchers zero ...

New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...

Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Germ cell tumors (GCTs) are a heterogeneous group of neoplasms that predominantly affect adolescents and young adults. Notably, geographical disparities in GCT incidence exist, with higher rates ...

Researchers discover that diverse genetic causes of autism converge on shared cell types and temporary maturation delays during early brain development.

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

A reanalysis of whole-genome data from 130 children conceived after the Chernobyl disaster has identified a statistically significant increase in a specific type of DNA mutation in the offspring of ...

Both males and females of all ages which were clinically and histopathologically confirmed for OSCC (Stage I-IV) were included in this study. Tissue biopsies were collected from patients meeting the ...

In a recent study published in the journal Nature, researchers at the Arc Institute describe the development and advantages of “Evo 2”. Evo 2 is a novel biological foundation model trained on a ...