Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

Scientists have pinpointed a protein in lysosomes that is involved in recycling a crucial fatty component of cell membranes to keep cells healthy. Researchers at Duke-NUS Medical School and colleagues ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, according to a Northwestern Medicine study published in the Journal of ...

Fukuoka, Japan—The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or ...

Because lysosome dysfunction is also a prominent feature of other neurodegenerative diseases, including Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis (ALS), this strategy eventually ...

Platinum nanoelectrodes measure reactive oxygen and nitrogen species emitted at a macrophage phagocytic cup, revealing how lysosomal pH modulates ROS/RNS flux during frustrated phagocytosis of a glass ...