During the October 20 episode of the Good Guys podcast, Stamos spoke with hosts Ben Soffer and Josh Peck about Loughlin and Giannulli’s split. The actor behind Uncle Jesse has been married to Caitlin McHugh, 39, since 2018, and they share a son, Billy, 7.

John Stamos is defending former “Full House” co-star Lori Loughlin amid her separation from Mossimo Giannulli after the estranged couple’s 2019 college admissions bribery scandal.