Deep brain stimulation can significantly reduce depressive symptoms in some individuals. Knowing what to expect before and after the procedure may help you determine if it’s right for you. Deep brain ...

Deep brain stimulation – implants in the brain that act as a kind of 'pacemaker' – has led to clinical improvements in half of the participants with treatment-resistant severe depression in an 'open ...

Anhedonia reduces the ability to feel joy and affects nearly 90% of people with major depression. Most conventional therapies ...

Many people with major depressive disorder get no relief from current treatments. Newer combinations of existing medications ...

Down in the dumps? Help might be hiding in your fridge. A new, first-of-its-kind study suggests a controversial diet could ease severe, drug-resistant depression — with improvements showing up in as ...

In patients with marked treatment-resistant depression (TRD), adjunctive vagus nerve stimulation (VNS) demonstrated sustained benefits in symptom, function, and quality of life (QOL) through 24 months ...

This is episode 2 of The Deep End. Listen to more episodes here. Depression can affect not just the mind, but the body, too. Inner experiences of mental struggles are private. But in this episode, Jon ...

Depression is a common mood disorder. It is completely normal for most people to feel sad or depressed at times as a reaction to loss or life’s challenges. But when depression leads to things like ...

The FDA has approved an esketamine nasal spray for the treatment of depression cases that do not respond to other therapeutic approaches. Image credit: Koldunov/Getty Images. Hundreds of millions of ...

New hope for earlier treatment might be on the horizon for people suffering the most severe form of depression. In a study of patients watching emotionally evocative movies, the responses of people ...

Salil Ankola receives treatment for severe depression as wife Ria supports his recovery journey.