Dysregulation of iron homeostasis plays a crucial role in retinal diseases, contributing to oxidative stress, inflammation, and ferroptosis, key processes that drive the degeneration of the retinal ...

Iron homeostasis is a tightly regulated mechanism, wherein the uptake, transport, storage and export of iron are stringently controlled. Dysregulation and excessive iron uptake lead to iron-dependent ...

Iron is an essential element that plays a crucial role in various cellular processes including enzymatic activity, DNA repair, and oxygen transfer. To determine an individual’s iron status, clinicians ...

Soluble transferrin receptor (sTfR) levels appeared to function as an inflammation-independent marker of iron status in patients with inflammatory bowel disease (IBD) and may help distinguish true ...

Transferrin is a glycoprotein with a molecular weight of 80 kDa, synthesized in the liver. Each transferrin molecule can bind up to two iron atoms for distribution to cells. The half-life of ...