Tuberculosis (TB) is one of the world's most common infectious diseases. Although infection with the Mycobacterium ...

A vaccine protects more than 100 million infants each year from severe tuberculosis (TB), including the fatal brain swelling it can cause in babies and toddlers. But the vaccine doesn't prevent adults ...

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the ...

Scientists at MIT have identified 24 protein fragments that could form a new tuberculosis vaccine, offering a potential breakthrough. This next-genera ...

Single-cell RNA sequencing identified distinct immune profiles in extrapulmonary TB, linking interferon–IL-1 signaling to ...

Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb), kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide.

Collaborative team from UMass Amherst and Seattle Children’s Research Institute uncovers how prior exposure to bacteria changes the lung’s innate immune response—and what it might mean for vaccines ...

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has ...

A live-attenuated tuberculosis (TB) vaccine candidate in development at Texas Biomedical Research Institute (Texas Biomed) elicits a much more balanced and effective immune response compared to the ...

Infection of the alveolar macrophages is tuberculosis's first step—what if we could change that? Credit: Alissa Rothchild Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills ...