A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing ...

DMBT1 is a multifunctional secreted protein that plays a pivotal role in the body’s first line of defence across mucosal surfaces. Characterised by its scavenger receptor cysteine-rich (SRCR) domains, ...

Intraepithelial lymphocytes (IELs) are a heterogeneous group of immune cells that reside within the epithelial layer of the intestine, forming a critical component of mucosal immunity. These cells ...

Early impairment of mucosal immunoglobulin A (IgA)-related immunity was associated with the later development of bronchiolitis obliterans syndrome (BOS) in lung transplant recipients; decreased ...

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines. Strategies to combat serious outbreaks of viral infections are particularly important. Such ...

A team of scientists, led by Duke-NUS Medical School, has discovered a potential intranasal vaccine candidate that provides improved, longer-lasting immunity against SARS-CoV-2 viruses compared to ...

A new study led by University of Toronto researchers has shown that immune cells in the gut follow an atypical pathway to produce antibodies that provide long-term protection against viruses. The ...

Oral vaccines promise painless, needle-free protection—but the human gut evolved to destroy exactly what vaccines are made of ...

Whooping cough, also known as pertussis, has re-emerged worldwide and continues to be a major health concern. Caused by the bacterium Bordetella pertussis, this contagious respiratory infection can ...

The COVID-19 pandemic highlighted the need for adaptable and scalable vaccine technologies. While mRNA vaccines have improved disease prevention, most are delivered by intramuscular injection, which ...

The rapid development of vaccines against SARS-CoV-2 has been a critical milestone in responding to the COVID-19 pandemic, yet the continued evolution of ...