Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...
Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 6 (Mar. 13, 2001), pp. 3068-3073 (6 pages) Cytochrome P450 14α-sterol demethylases (CYP51) are essential ...
A research group is studying disease resistance in tuberculosis. The group has described the structure of a regulator that controls the expression of a pump that removes toxins from the bacteria.
Ting-Wan Lin, Melrose M. Melgar, Daniel Kurth, S. Joshua Swamidass, John Purdon, Teresa Tseng, Gabriela Gago, Pierre Baldi, Hugo Gramajo, Shiou-Chuan Tsai Proceedings of the National Academy of ...
Tuberculosis (TB) is one of the world's most common infectious diseases. Although infection with the Mycobacterium ...
The number of people diagnosed with tuberculosis worldwide rose again last year, eclipsing 2023's record total.
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