Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...
Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 6 (Mar. 13, 2001), pp. 3068-3073 (6 pages) Cytochrome P450 14α-sterol demethylases (CYP51) are essential ...
A research group is studying disease resistance in tuberculosis. The group has described the structure of a regulator that controls the expression of a pump that removes toxins from the bacteria.
Ting-Wan Lin, Melrose M. Melgar, Daniel Kurth, S. Joshua Swamidass, John Purdon, Teresa Tseng, Gabriela Gago, Pierre Baldi, Hugo Gramajo, Shiou-Chuan Tsai Proceedings of the National Academy of ...
AMES, Iowa – Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally ...
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