The buzz is building for NASA’s Artemis II mission that will send four astronauts on a 10-day voyage around the moon. The highly anticipated endeavor will be the first crewed moon-bound flight since the final Apollo mission way back in 1972.

The four people preparing to fly around the Moon on Artemis II are already living as if launch day has begun. Long before they strap into Orion, their bodies, immune systems, and exposure to germs are being managed as tightly as any rocket valve or guidance computer.