Scientists at Ghent University have created a mouse model that incorporates human versions of the receptors that recognize the fragment crystallizable region of immunoglobulin G, one of the most ...

Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...

A bitter taste has always been considered a warning signal, devoted to protecting us from ingesting potentially harmful ...

T cell receptors (TCRs) are fundamental to the adaptive immune system, playing a pivotal role in recognising and responding to pathogenic challenges. Generated through the process of V(D)J ...

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...

Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...

Phase I Evaluation of Prolonged-Infusion Gemcitabine With Irinotecan for Relapsed or Refractory Leukemia or Lymphoma ABSTRACT: Androgen receptor (AR) is a member of the steroid hormone receptor family ...

"I think PAGER has potential for impact, both in the G protein coupled receptor biology field, and in synthetic circuits or cell-based therapies," said Alice Ting, professor of genetics at the School ...

Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and ...

A new study led by the University of Miami Miller School of Medicine's Kirill Martemyanov, Ph.D., and international ...