A variety of strategies have been designed to modulate redox levels. Chemotherapy, radiotherapy, and nanoparticles that generate ROS result in oxidative damage and immunogenic cell death at tumor ...

Pyruvate dictates redox balance and cell size, establishing metabolism as a dominant regulator of cellular fitness, unveiling new strategies to modulate cancer, regeneration, and diabetes.

Zuen Ren, Huizhi Liang, Phillip M. Galbo Jr, Malindrie Dharmaratne, Ameya S. Kulkarni, Atefeh Taherian Fard, Marie Louise Aoun, Nuria Martinez-Lopez, Kimita Suyama ...

Following cisplatin's success in the treatment of cancer, numerous other platinum-based complexes have been investigated as ...