A method is described that can predict the way the great majority of polyolefins mix with each other just based on knowledge of their chemical architecture. The miscibility of saturated hydrocarbon ...

For many decades, limited aqueous solubility is a major difficulty affecting 40% of marketed and 60% of newly reported drug candidates 1,2. This limitation not only hinders the drug absorption but ...

The international collaborative team of Tokyo University of Agriculture and Technology (TUAT, Japan), IIT Ropar (India), Osaka Univ. (Japan) has discovered that "partially miscibility," in which two ...

Pharmaceutical companies, equipment providers, contract-service providers, and excipient manufacturers apply various approaches for improving solubility. The article examines some recent developments.

Solubility, polymorphism, crystallinity, and crystal habit of acetaminophen and racemic (+/-)-ibuprofen were determined by initial screening of 23 solvents for scale-up. Solubility curves were ...

A technique first described back in the 1960’s, differential scanning calorimetry (DSC), is still a mainstay of drug-polymer miscibility analysis in most pharmaceutical research groups. Now, a new ...