Drug solubility can benefit from approaching solubility issues early on in the drug lifecycle. Currently, a significant proportion of drugs that are approved or in the development pipeline are poorly ...

The poor water solubility of newly discovered medicines has been a major issue for pharmaceutical industry, and various techniques have been explored and developed to enhance the solubility of drugs ...

Controlling protein solubility is critical yet challenging for food and pharmaceutical applications. This review dissects the molecular and environmental determinants governing solubility behavior. It ...

High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...

Key concepts Chemistry Solubility Water Temperature Introduction Have you ever mixed sand and salt together and wondered how you could separate them again? If you had to separate them, would you have ...