Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans. Not well defined stress conditions are known to wake up these parasites ...

When viral DNA is more “liquidy,” it is more easily injected into host cells—so easily, in fact, that multiple virus-carrying capsids may squeeze their DNA payloads into a host cell simultaneously.

Kaposi's sarcoma-associated herpesvirus (KSHV) is strongly linked to Kaposi's sarcoma, primary effusion lymphomas, and a subset of multicentric Castleman's disease. The mechanism by which this virus ...

The oncogenic herpesvirus (HHV8 or KSHV) causes a cancer known as Kaposi's Sarcoma. An international team of scientists led by the University of Helsinki has discovered key factors that control the ...

In a recent study published in the journal PLoS Pathogens, researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli (AIEC) to better understand their behavior in vitro ...

Future Microbiol. 2012;7(10):1191-1205. Another viral lytic gene product, vIRF4, was recently identified to be a novel interaction partner of RBP-Jκ. vIRF4 binds the hydrophobic pocket of RBP-Jκ ...

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median ...

“To completely cure HSV-1, the idea is to prevent the virus from going into latency, because then, it’s protected by our own bodies,” said Esther González-Almela, a virologist at the Guangdong Academy ...

A study has identified a binding protein in cancer cell's nucleus, known as CHD4, as a critical agent keeping Kaposi's sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body's immune ...

Scientists have discovered a potential target for gastric cancers associated with Epstein-Barr Virus. Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers ...