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NFL DFS picks for Week 2 featuring top plays, value targets and lineup strategy to help you build winning rosters on DFS for Yahoo.
SportsLine's model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. One of its favorite picks at the best betting apps is the Buccaneers (-8.5, 40.5) covering versus Cleveland, which cashes well over 50% of the time. You can find the model's picks for every NFL Week 2 game here .
Week 1 gave everyone a small mountain of data to sort through, new coaching staffs, backfields that already look different than they did in August, and a few quarterback situations that got messier instead of clearer. Below are 11 plays worth building around on this week's main slate, broken down by position with the reasoning behind each one.
David Montgomery and these four players round out the top-five underrated fantasy football NFL DFS GPP plays in Week 2.
SportsLine's model has analyzed the Week 2 NFL schedule and locked in its Week 2 NFL picks, predictions
PM ET FanDuel odds: Panthers -2.5, total 43.5Series History: The Falcons lead the all-time series (37-25), but the Panthers have won four of the past five.
Your weekly blueprint for building winning tournament lineups on DraftKings.
Josh Allen and these five players round out the perfect Week 2 NFL DFS showdown lineup on DraftKings for Thursday Night Football between the Bills and Lions.