Autoimmune hepatitis (AIH) is a complex, chronic inflammatory liver disorder in which the body's immune system aberrantly targets hepatocytes, leading to progressive hepatic injury. Characterised by ...

Autoimmune hepatitis quietly damages the liver for years before symptoms appear; specialists in Kenya warn of late diagnoses and urge early medical checks. [File, Standard] When people think about ...

The principle of therapy for chronic inflammatory liver diseases is the removal of causal agents. For autoimmune liver diseases, however, total removal of causal agents and immune cells is impossible.

Corticosteroid therapy is effective in all forms of autoimmune hepatitis, and the combination of prednisone and azathioprine is preferred. Remission can be achieved in 80% of patients within 3 years, ...

Tacrolimus binds to the intracellular protein FKBP12, forming a complex that specifically inhibits calcineurin, a protein phosphatase essential for activating the transcription factor NFAT. By ...

As the largest internal organ in the human body, the liver supports a wide range of responsibilities related to metabolism, immunity, digestion, detoxification, vitamin storage, and other functions.

A combination of silybin and carvedilol for treating liver fibrosis is more effective than either drug alone. | Drug ...

The American Association for the Study of Liver Diseases and Infectious Diseases Society of America have updated guidance on ...

AIH with AITD, T1DM, UC, Crohn disease, and celiac disease appear to be significant. However, associations between AIH and PSC/PBC, RA, SLE, SS, and vitiligo are not well-supported. Diagnostic ...

Scientists have found that combining silybin with carvedilol works far better against liver fibrosis than either drug alone.