Original research: Mortality associated with moderate and severe mitral regurgitation in 608 570 men and women undergoing ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with persistent undertreatment of high-risk older patients with effective ...

Implantation of drug-eluting stents (DESs) remains central to percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS) and chronic coronary syndromes (CCS). DES platforms, polymers ...

Introduction Cardiovascular diseases (CVD) accounted for an alarming 17.9 million deaths globally in 2019. Acute coronary syndrome (ACS) is often the most common initial presentation of CVD. ACS ...

2 Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 3 Epidemiological Cardiology Research Center (EPICARE), Department of Epidemiology and ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergency surgery to avert fatal outcome. Conventional surgical procedures comprise excision of the entry tear and ...

Objective Troponin and B-type natriuretic peptide (BNP) concentrations are associated with cardiovascular risk in stable patients. Understanding their determinants and identifying modifiable clinical ...

Introduction Pulmonary vein isolation (PVI) is an established therapeutic strategy for atrial fibrillation (AF). Recent advancements in AF ablation have led to the development of the novel pulsed ...

Diabetes is an increasing problem in sub-Saharan Africa. Type 2 diabetes, the most common form, is becoming more prevalent owing to rising rates of obesity, physical inactivity and urbanisation. Type ...

Correspondence to Dr Carol Ann Remme, Amsterdam UMC Location AMC, 1105 AZ Amsterdam, The Netherlands; c.a.remme{at}amsterdamumc.nl Brugada syndrome (BrS) is an inherited cardiac disorder, ...

Objective To study the utility of body fat percentage in predicting health outcomes when other obesity indices are considered. Methods We conducted a prospective cohort study to evaluate the ...