A mobile state of the kinesin–ADP head is discovered using multi- and single-molecule fluorescence polarization. The structure of the microtubule–kinesin complex has been determined by cryo-EM. The ...

Kinesin is an ATP-driven molecular motor protein that moves processively along microtubules. Despite considerable research, the detailed mechanism of kinesin motion remains elusive. We applied an ...

Researchers at Gifu University’s Institute for Glyco-core Research have developed two synthetic approaches to produce a fragment of a molecule called poly(ADP-ribose). By developing two ways to ...

Phase I trial involving the pharmacodynamic (PD) study of circulating tumour cells, of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), with docetaxel ...

You may not know what it is, but you burn more than your body weight of it every day. Adenosine triphosphate (ATP), a tiny molecule that packs a powerful punch, is the primary energy source for most ...