4 Department of Cardiothoracic Surgery, Royal Brompton Hospital and Imperial College, London, UK Correspondence to Dr Dipak Kotecha, Clinical Trials and Evaluation Unit, Royal Brompton Hospital, ...

Vagally mediated atrioventricular (AV) block is defined as a paroxysmal AV block, localised within the AV node, associated with slowing of the sinus rate. All types of second-degree AV block, ...

For patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, iron deficiency is common and associated with more severe symptoms, worse quality of life and an ...

Positron emission tomography (PET) imaging is useful in cardiovascular disease across several areas, from assessment of myocardial perfusion and viability, to highlighting atherosclerotic plaque ...

5 Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore 6 Department of Cardiology, National University Heart Centre, Singapore Objective To investigate the prognostic ...

Atrial fibrillation (AF), which is the most diagnosed arrhythmia, is becoming a significant issue for health policy-makers. In particular, more and more attention is being devoted to AF prevention.

Background The Assessing cardiovascular risk using Scottish Intercollegiate Guidelines Network (ASSIGN) risk score, developed in 2006, is used in Scotland for estimating the 10-year risk of first ...

Introduction Current guidelines recommend surgical or transcatheter aortic valve replacement (AVR) for severe aortic stenosis (AS) once symptoms or left ventricular dysfunction develop, whilst those ...

Objective In the majority of studies, the effect of physical activity (PA) on cardiovascular disease (CVD) and mortality is estimated at a single time point. The impact of long-term PA is likely to ...

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Background For the treatment of breathlessness in heart failure (HF), most textbooks advocate the use of opioids. Yet, meta-analyses are lacking. Methods A systematic review was performed for ...

Objective We retrospectively analysed outcome data from the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study to assess the incidence and potential risk factors of sudden cardiac death (SCD) ...