A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

Trainees’ paths to safe, independent practice are variable. Artificial intelligence could help accelerate implementation of competency-based medical education to support individualized development.

When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.

Beyond being a rare federal program focused on stabilizing rural health care services, the Rural Health Transformation Program represents a vehicle for advancing the administration’s health priorities ...

Recent court decisions have treated statements in drug labels as evidence of patent infringement by generic-drug manufacturers. The Supreme Court has an opportunity to address this trend.

We conducted a trial involving the release of male A. aegypti mosquitoes infected with the wAlbB strain of wolbachia bacteria for the control of dengue in Singapore, a tropical city-state. In this ...

A 60-year-old man presented with a 15-day history of generalized weakness and right upper abdominal pain. Imaging studies revealed diffuse disruption of the hepatic architecture by hyperechoic nodules ...

To the Editor: We have several concerns with regard to the ASCENT-03 trial by Cortés et al. (Nov. 13 issue). 1 First is the use of physician’s choice in determining the chemotherapy regimen for the ...

It is widely accepted that incident cardiovascular events in persons with a history of major atherosclerotic cardiovascular disease are largely preventable. 1,2 Most cardiovascular risk can be ...

During the 6-year period, 7901 deaths occurred. The leading cause of maternal death was unintentional drug overdose (1152 deaths; 5.2 deaths per 100,000 live births). Violence (defined as homicide or ...