Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked ...

School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China Bioassay-guided isolation of spiroaspertrione A from cultures of Aspergillus sp. TJ23 in 2017 demonstrated potent ...

Amine acid transformation is an important chemical process in biological systems. As a well-developed and acknowledged tool, chiral aldehyde catalysis provides good catalytic activation and ...

The Thermo Scientific picoSpin 45 NMR spectrometer is a useful tool for teaching through the aldol condensation reaction. In a number of undergraduate organic teaching programs, probably the first ...

Neutron protein crystallography can visualize bound hydrogen (H) atoms and protons across entire structures, which are generally invisible by X-ray crystallography. In all X-ray crystal structures of ...

Ketones are in equilibrium with a form known as an enol. The name enol derives from the fact that enols are a combination of a carbonyl (C=O) containing group, such as an aldehyde or ketone and an ...

Alkynyl ketones are attractive but challenging nucleophiles in enolate chemistry. Their susceptibility to other reactions such as Michael additions and the difficulty of controlling the enolate ...

The dark blue to pink-orange transformation revolves around astaxanthin, a carotenoid, and its interaction with a protein called crustacyanin that lobsters accumulate by feeding on plankton.

When amides get out of shape, a whole new world of asymmetric aldol reactions opens up, says Karl Collins When I think of asymmetric aldol reactions, what immediately springs to mind is using boron to ...