The goal of the study is to investigate host genetic and immunologic predictors of resistance to M. tuberculosis infection and progression from latent M. tuberculosis infection to active tuberculosis ...

Signal transduction across membranes through regulated intramembrane proteolysis is conserved throughout all domains of life. In the SREBP pathway of human cells, the membrane-bound SREBP ...

Physician-scientist Michael Glickman aims to understand how infections develop by investigating the physiology and pathogenic mechanisms of mycobacteria. We spoke with Dr. Glickman about his work in ...

This is a preview. Log in through your library . Abstract Background. Tuberculosis is an urgent public health problem caused by Mycobacterium tuberculosis infection. Many factors, including host ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis (M. tuberculosis), is deadly in ...

Immunotherapy. 2012;4(6):629-647. This review introduces the disease, particularly the complex interaction of M. tuberculosis with the host's immune system, as background to understanding the ...

1 Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India 2 Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, ...