4 Department of Cardiothoracic Surgery, Royal Brompton Hospital and Imperial College, London, UK Correspondence to Dr Dipak Kotecha, Clinical Trials and Evaluation Unit, Royal Brompton Hospital, ...

Vagally mediated atrioventricular (AV) block is defined as a paroxysmal AV block, localised within the AV node, associated with slowing of the sinus rate. All types of second-degree AV block, ...

For patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, iron deficiency is common and associated with more severe symptoms, worse quality of life and an ...

Positron emission tomography (PET) imaging is useful in cardiovascular disease across several areas, from assessment of myocardial perfusion and viability, to highlighting atherosclerotic plaque ...

5 Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore 6 Department of Cardiology, National University Heart Centre, Singapore Objective To investigate the prognostic ...

Background The Assessing cardiovascular risk using Scottish Intercollegiate Guidelines Network (ASSIGN) risk score, developed in 2006, is used in Scotland for estimating the 10-year risk of first ...

Objective In the majority of studies, the effect of physical activity (PA) on cardiovascular disease (CVD) and mortality is estimated at a single time point. The impact of long-term PA is likely to ...

Background For the treatment of breathlessness in heart failure (HF), most textbooks advocate the use of opioids. Yet, meta-analyses are lacking. Methods A systematic review was performed for ...

Objective: To determine the accuracy of assessing cardiovascular disease (CVD) risk in the primary prevention of CVD and its impact on clinical outcomes. Design: Systematic review. Data sources: ...

Objective A systematic review and meta-analysis was conducted to assess the efficacy of low-sodium salt substitutes (LSSS) as a potential intervention to reduce cardiovascular (CV) diseases. Methods ...

Objectives This updated hierarchical Bayesian meta-analysis aims to integrate the latest randomised controlled trials (RCTs) on the use of cerebral embolic protection (CEP) in transcatheter aortic ...

In his song ‘Envelhecer’ (‘Aging’), Arnaldo Antunes states that “the most modern thing there is in this life is to grow old”.1 In this piece, he reframes aging not only as an inevitable biological ...